Table 2 Relative risk estimates for REN (A) and AGT (B) haplotypes

C-T-A

58.3

0.39 (0.18-0.84); 0.02

0.60 (0.24-1.51); 0.28

C-c-g

20.9

1.42 (0.65-3.12); 0.38

3.00 (0.93-9.93); 0.07

t-c-g

20.4

1.46 (0.66-3.20); 0.35

4.63 (1.46-14.7); 0.01

B: Relative risk estimates (95% CI; p-value) for fetal REN haplotypes (n = 90 family triads)

REN haplotype

Frequency (%)

Single dose

Double dose

A-G-C

59.5

0.63 (0.27-1.46); 0.27

0.36 (0.13-0.98); 0.05

A-t-C

31.6

0.86 (0.37-1.95); 0.72

0.40 (0.12-1.39); 0.15

c-G-t

8.5

1.45 (0.66-3.19); 0.35

Not estimable