Table 3 Comparisons of serological biomarkers in the dominant model and recessive model

Dominant model of RS4977574

AA

AG + GG

Statistical parameter

P value

CKMB (U/L)

16 (12.1–21)

17 (13–22)

− 1.925

0.054

TC (mmol/L)

4.64 (3.75–5.61)

4.62 (3.92–5.43)

− 0.267

0.789

TG (mmol/L)

1.68 (1.13–2.43)

1.82 (1.25–2.49)

− 1.761

0.078

HDL (mmol/L)

1.41 (1.15–1.67)

1.36 (1.12–1.62)

−1.059

0.290

LDL (mmol/L)

2.71 (2.14–3.53)

2.79 (2.22–3.42)

−0.658

0.510

ApoA (g/L)

1.30 (1.16–1.46)

1.29 (1.14–1.46)

−1.038

0.299

ApoB (g/L)

0.91 ± 0.24

0.92 ± 0.22

0.547

0.585

Glu (mmol/L)

5.09 (4.59–6.07)

5.07 (4.62–5.90)

− 0.075

0.940

Bun (mmol/L)

4.94 (3.96–5.80)

4.87 (4.06–5.88)

− 0.150

0.881

Cre (μmol/L)

70 (62–79.75)

71 (62–82)

−0.547

0.584

Recessive model of RS4977574

GG

AA+AG

Statistical parameter

P value

CKMB (U/L)

17 (13–22)

17 (13–21)

−0.281

0.779

TC (mmol/L)

4.61 (3.93–5.48)

4.63 (3.88–5.48)

−0.306

0.760

TG (mmol/L)

1.85 (1.26–2.41)

1.75 (1.20–2.50)

−1.060

0.289

HDL (mmol/L)

1.32 (1.10–1.62)

1.38 (1.15–1.64)

− 1.697

0.090

LDL (mmol/L)

2.83 (2.26–3.45)

2.74 (2.15–3.43)

−1.348

0.187

ApoA (g/L)

1.27 (1.13–1.42)

1.30 (1.16–1.48)

−2.191

0.028

ApoB (g/L)

0.90 ± 0.21

0.92 ± 0.23

−1.168

0.243

Glu (mmol/L)

5.04 (4.55–5.80)

5.07 (4.62–6.03)

−1.072

0.284

Bun (mmol/L)

4.87 (4.02–5.61)

4.89 (4.06–5.94)

−1.349

0.177

Cre (μmol/L)

69 (61–81)

71 (62–81)

−1.469

0.142

Dominant model of RS1333045

CC

TC + TT

Statistical parameter

P value

CKMB (U/L)

17 (13–22)

16 (13–21)

−0.628

0.530

TC (mmol/L)

4.62 (3.91–5.51)

4.63 (3.88–5.48)

− 0.372

0.710

TG (mmol/L)

1.90 (1.27–2.47)

1.73 (1.18–2.48)

− 1.807

0.071

HDL (mmol/L)

1.32 (1.11–1.62)

1.38 (1.14–1.64)

−1.469

0.142

LDL (mmol/L)

2.94 (2.27–3.51)

2.73 (2.14–3.40)

−2.147

0.032

ApoA (g/L)

1.27 (1.13–1.43)

1.30 (1.16–1.48)

−1.970

0.049

ApoB (g/L)

0.90 ± 0.21

0.92 ± 0.23

−0.989

0.323

Glu (mmol/L)

5.07 (4.57–5.79)

5.07 (4.62–6.03)

−0.915

0.360

Bun (mmol/L)

4.93 (4.04–5.78)

4.87 (4.06–5.90)

−0.612

0.541

Cre (μmol/L)

69 (61–81)

71 (62–81)

−1.175

0.240

Recessive model of RS1333045

TT

TC + CC

Statistical parameter

P value

CKMB (U/L)

16 (12.4–21)

17 (13–21.48)

−1.252

0.210

TC (mmol/L)

4.60 (3.74–5.62)

4.65 (3.92–5.44)

− 0.159

0.873

TG (mmol/L)

1.71 (1.15–2.46)

1.81 (1.24–2.48)

− 1.131

0.258

HDL (mmol/L)

1.38 (1.13–1.67)

1.36 (1.12–1.62)

− 0.641

0.521

LDL (mmol/L)

2.64 (2.09–3.48)

2.79 (2.22–3.43)

−1.220

0.223

ApoA (g/L)

1.29 (1.15–1.46)

1.29 (1.14–1.46)

−0.233

0.816

ApoB (g/L)

0.91 ± 0.25

0.92 ± 0.22

−0.576

0.565

Glu (mmol/L)

5.10 (4.59–6.04)

5.05 (4.62–5.92)

− 0.401

0.688

Bun (mmol/L)

4.85 (3.91–5.74)

4.90 (4.06–5.89)

−0.941

0.347

Cre (μmol/L)

71 (62.8–80)

71 (61.05–81)

−0.026

0.979