Table 6 Association between DNMT3A polymorphisms and number of methylated genes in the whole population and in patients infected with HP

rs6733868

CC

CG

GG

CC

CG

GG

 0 (123)

36

57

30

reference

17

22

14

reference

 1 or 2 (287)

117

135

35

0.59 (0.37–0.94); p = 0.026

69

89

20

0.74 (0.38–1.42); p = 0.36

 3 or 4 (100)

59

32

9

0.34 (0.18–0.64); p < 0.0001

56

26

8

0.26 (0.12–0.55); p = 0.0004

OR (95% C.I.); p value

OR (95% C.I.); p value

rs13428812

AA

AG

GG

AA

AG

GG

 0 (123)

57

53

13

reference

26

21

6

reference

 1 or 2 (287)

175

100

12

0.55 (0.36–0.85); p = 0.0073

107

67

4

0.61 (0.32–1.13); p = 0.12

 3 or 4 (100)

81

13

6

0.22 (0.11–0.44); p < 0.0001

74

11

5

0.18 (0.083–0.41); p < 0.0001