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Table 4 Comparison of studied according to IL-6 genotypes in all osteoarthritis cases

From: The IL-6 rs12700386 polymorphism is associated with an increased risk of developing osteoarthritis in the knee in the Chinese Han population: a case-control study

OA(n = 351)

IL-6 rs12700386

 

GG(n = 193)

GC(n = 134)

CC(n = 24)

P

GC + CC(n = 158)

P

GG + GC(n = 327)

P

ESR, mm/h

Mean ± SD

18.14 ± 10.61

18.82 ± 8.40

19.29 ± 8.33

0.065

18.89 ± 8.37

0.468

18.42 ± 9.76

0.558

CRP, mg/L

Mean ± SD

20.29 ± 14.16

19.49 ± 15.06

17.96 ± 14.41

0.509

19.25 ± 14.74

0.505

19.96 ± 14.52

0.477

VAS

Mean ± SD

5.64 ± 1.51

5.75 ± 1.57

5.50 ± 2.06

0.262

5.71 ± 1.65

0.698

5.69 ± 1.54

0.671

Lequesnes’ index

Mean ± SD

14.38 ± 2.04

14.70 ± 2.12

14.46 ± 1.79

0.539

14.66 ± 2.07

0.204

14.51 ± 2.08

0.144

Affected leg

Left/right, n

117/76

81/53

16/8

0.838

97/61

0.913

198/129

0.667

KL grading

III+ IV/II, n

107/86

82/52

11/13

0.305

93/65

0.588

190/138

0.288

  1. SD Standard Deviation; Bold values are statistically significant (P < 0.05)
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BMC Medical Genetics

ISSN: 1471-2350

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