| rs7754840 | P | rs7138803 | P | rs6548238 | ||||
---|---|---|---|---|---|---|---|---|---|
CC + CG | GG | AA+AG | GG | CC + CT | TT | P | |||
Waistcircumference (cm) | 96.68 ± 17.31 | 90.29 ± 14.56 | 0.040 | 97.11 ± 16.42 | 92.53 ± 16.53 | 0.139 | 97.27 ± 16.84 | 90.75 ± 15.66 | 0.030 |
Waist/hip ratio | 1.11 ± 0.36 | 0.97 ± 0.25 | 0.027 | 1.09 ± 0.30 | 1.04 ± 0.35 | 0.345 | 1.15 ± 0.33 | 0.95 ± 0.29 | 0.001 |
BMI (kg/m2) | 26.48 ± 4.98 | 25.98 ± 5.80 | 0.612 | 27.94 ± 4.94 | 25.25 ± 5.25 | 0.006 | 26.94 ± 4.57 | 22.52 ± 5.98 | 0.023 |
FPG (mmol/L) | 10.07 ± 4.00 | 10.14 ± 3.67 | 0.925 | 10.97 ± 3.77 | 9.54 ± 3.85 | 0.046 | 11.01 ± 3.80 | 9.01 ± 3.69 | 0.004 |
HbA1c, % | 9.90 ± 3.94 | 9.72 ± 3.36 | 0.799 | 10.30 ± 3.74 | 9.53 ± 3.70 | 0.268 | 10.70 ± 4.02 | 8.78 ± 3.05 | 0.004 |
SBP (mm Hg) | 132.91 ± 23.98 | 124.93 ± 17.85 | 0.039 | 130.00 (112.00,115.00) | 122.00 (110.00,150.00) | 0.413 | 131.39 ± 22.03 | 128.20 ± 22.39 | 0.432 |
DBP (mm Hg) | 84.03 ± 11.14 | 82.13 ± 10.60 | 0.360 | 86.45 ± 9.91 | 81.34 ± 11.16 | 0.012 | 85.91 ± 9.91 | 80.22 ± 11.39 | 0.004 |
TG (mmol/L) | 4.61 ± 4.38 | 4.32 ± 3.69 | 0.705 | 3.66 (1.98,7.13) | 2.62 (1.42,4.84) | 0.041 | 5.46 ± 4.80 | 3.36 ± 2.76 | 0.005 |
TC (mmol/L) | 5.39 ± 2.60 | 5.38 ± 2.60 | 0.44 | 5.38 ± 2.60 | 4.93 ± 2.38 | 0.324 | 5.88 ± 2.45 | 4.51 ± 1.99 | 0.001 |
HDL-C (mmol/L) | 1.05 ± 0.54 | 0.98 ± 0.47 | 0.455 | 0.92 (0.58,1.06) | 0.97 (0.70,1.22) | 0.066 | 0.85 ± 0.36 | 1.23 ± 0.59 | 0.001 |
LDL-C (mmol/L) | 2.92 ± 1.01 | 2.37 ± 0.87 | 0.176 | 2.99 ± 0.93 | 2.72 ± 0.98 | 0.133 | 2.98 ± 1.04 | 2.63 ± 0.85 | 0.050 |
FINS (μIU/mL) | 22.27 ± 17.33 | 17.82 ± 10.06 | 0.076 | 19.60 (16.56,26.72) | 13.18 (8.72,26.10) | 0.007 | 21.50 ± 12.51 | 19.55 ± 17.88 | 0.484 |
HOMA-IR | 6.81 (2.98,14.05) | 5.60 (3.59,13.86) | 0.677 | 10.46 (3.72,15.07) | 5.35 (2.90,12.68) | 0.083 | 10.01 ± 8.52 | 8.79 ± 7.31 | 0.399 |
HOMA-IS | 0.010 (0.000,0.020) | 0.010 (0.005,0.017) | 0.184 | 0.012 (0.010,0.020) | 0.010 (0.000,0.020) | 0.662 | 0.010 (0.000,0.010) | 0.016 (0.010,0.020) | 0.001 |