Variable (no. of study) | D vs. I | DD vs. II | ID vs. II | ID + DD vs. II | DD vs. II + ID |
---|---|---|---|---|---|
OR (95%CI), I2 (%), Ph | OR (95%CI), I2 (%), Ph | OR (95%CI), I2 (%), Ph | OR (95%CI), I2 (%), Ph | OR (95%CI), I2 (%), Ph | |
Overall (16) | 0.96 (0.82, 1.12), 74, < 0.00001 | 0.99 (0.73, 1.36), 71, < 0.00001 | 0.81 (0.72, 0.91), 42, 0.04 | 0.91 (0.73, 1.13), 64, 0.0003 | 1.05 (0.85, 1.30), 61, 0.0007 |
Ethnicity | |||||
East Asian (4) | 0.95 (0.68, 1.32),86, < 0.0001 | 0.99 (0.51, 1.93), 84, 0.0004 | 0.82 (0.61, 1.10), 63, 0.05 | 0.86 (0.59, 1.25), 79, 0.003 | 1.09 (0.65, 1.84), 77, 0.005 |
Caucasian (12) | 0.96 (0.79, 1.17), 70, 0.0001 | 0.99 (0.68, 1.45), 67, 0.0005 | 0.82 (0.69, 0.97), 39, 0.08 | 0.95 (0.71, 1.27), 59, 0.004 | 1.03 (0.81, 1.32), 57, 0.007 |
Psoriasis subtype | |||||
Arthritis (4) | 0.83 (0.61, 1.12), 66, 0.03 | 0.69 (0.52, 0.91), 49, 0.12 | 0.66 (0.50, 0.85), 0, 0.78 | 0.67 (0.52, 0.86), 8, 0.35 | 1.04 (0.73, 1.48), 53, 0.09 |
Vulgaris (5) | 1.12 (0.77, 1.65), 65, 0.02 | 1.29 (0.62, 2.68), 63, 0.03 | 1.19 (0.65, 2.21), 60, 0.04 | 1.29 (0.64, 2.63), 71, 0.009 | 1.02 (0.76, 1.37), 0, 0.48 |
Source of controls | |||||
Hospital-based (9) | 0.84 (0.68, 1.04),72, 0.0004 | 0.84 (0.55, 1.29), 68, 0.002 | 0.77 (0.67, 0.90), 23, 0.24 | 0.80 (0.61, 1.04), 56, 0.02 | 0.97 (0.71, 1.32), 58, 0.01 |
Others (7) | 1.12 (0.88, 1.42), 77, 0.0003 | 1.22 (0.74, 2.01), 77, 0.0002 | 1.00 (0.72, 1.40), 59, 0.02 | 1.11 (0.75, 1.64), 72, 0.001 | 1.14 (0.83, 1.56), 68, 0.005 |
Caucasian population | |||||
Arab (4) | 1.04 (0.52, 2.06), 75, 0.008 | 1.65 (0.91, 3.00), 2, 0.38 | 1.43 (0.81, 2.53), 0, 0.47 | 1.56 (0.93, 2.62), 7, 0.36 | 1.41 (0.89, 2.23), 0, 0.68 |
Europe (4) | 0.94 (0.81, 1.10), 21, 0.28 | 0.85 (0.62, 1.16), 18, 0.30 | 0.84 (0.63, 1.12), 47, 0.13 | 0.84 (0.64, 1.10), 48, 0.13 | 0.99 (0.79, 1.24), 4, 0.37 |
Other (Iran, Pakistan, and Turkey) (4) | 0.93 (0.64, 1.34), 85, 0.0001 | 0.83 (0.38, 1.84), 86, < 0.0001 | 0.73 (0.58, 0.92), 41, 0.17 | 0.82 (0.49, 1.36), 75, 0.007 | 0.97 (0.57, 1.66), 84, 0.0003 |