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Table 5 IKZF-1 haplotypes distributions in cases and controls

From: IKZF1 genetic variants rs4132601 and rs11978267 and acute lymphoblastic leukemia risk in Tunisian children: a case-control study

Haplotypea

Cases

Controls

P

OR b (95% CI)

aP

aOR b (95% CI)

T A

0.571 c

0.690

–

1.00 (Reference)

–

1.00 (Reference)

G A

0.256

0.193

0.053

1.58 (1.00–2.51)

0.046

1.61 (1.01–2.57)

G G

0.1

0.068

0.095

1.77 (0.91–3.46)

0.089

1.8 (0.92–3.55)

T G

0.071

0.047

0.33

1.43 (0.69–2.96)

0.37

1.4 (0.68–2.89)

  1. a Haplotype containing rs4132601 T/G and rs11978267 A/G
  2. b aP; aOR adjusted odds ratio; covariates that were controlled for were age and gender
  3. c Haplotype frequency determined by the maximum likelihood method
  4. Bold-faced values are indicating a significant association