Table 1 Laboratory findings in the patients showing increased Alk-P, AFP, and blood tyrosine levels in all affected individuals
Variable | Patient I | Patient II | Patient III |
|---|---|---|---|
AST (Reference range: < 60 U/L) | 942 | 241 | 176 |
ALT (Reference range: < 45 U/L) | 554 | 106 | 61 |
Alk-P (Reference range: 124–341 U/L) | 1274 | 897 | 2700 |
AFP (Reference range: 0–97 ng/mL) | 16,372 | 291 | > 2000 |
Total Bilirubin (Reference range: < 1.9 mg/dL) | 12.8 | 11.9 | 10.5 |
Direct Bilirubin (Reference range: < 0.2 mg/dL) | 3.2 | 4.7 | 3.9 |
PT (Reference range: 10.5–11.5 s) | > 60 | 21.8 | 34 |
PTT (Reference range: 24–36 s) | 58 | 59 | 58 |
Blood tyrosine (Reference range: 20–100 μmol/L) | 240 | 176 | 309 |
Blood succinylacetone (Reference range: < 5.0 mcM) | < 5.0 | < 5.0 | < 5.0 |