Table 4 Association of SNPs with risk of stroke based on logistic tests adjusted by gender and age
From: Genetic variants in CYP4F2 were significantly correlated with susceptibility to ischemic stroke
SNP-ID | Model | Genotype | No. (frequency) | Adjusteda | ||
|---|---|---|---|---|---|---|
Case | Control | OR (95% CI) | pb-value | |||
rs3093203 | codominant | G/G | 275 (57.7%) | 292 (59.2%) | 1.00 | – |
A/G | 180 (37.7%) | 178 (36.1%) | 1.07 (0.82–1.41) | 0.614 | ||
A/A | 22 (4.6%) | 23 (4.7%) | 0.90 (0.48–1.69) | 0.737 | ||
dominant | G/G | 275 (57.7%) | 292 (59.2%) | 1.00 | – | |
A/G-A/A | 202 (42.3%) | 201 (40.8%) | 1.02 (0.82–1.27) | 0.868 | ||
recessive | G/G-A/G | 455 (95.4%) | 470 (95.3%) | 1.00 | – | |
A/A | 22 (4.6%) | 23 (4.7%) | 1.05 (0.81–1.37) | 0.706 | ||
log-additive | – | – | – | 0.87 (0.47–1.63) | 0.670 | |
rs3093193 | codominant | C/C | 216 (45.3%) | 248 (50.2%) | 1.00 | – |
G/C | 213 (44.7%) | 208 (42.1%) | 1.14 (0.87–1.50) | 0.342 | ||
G/G | 48 (10.01) | 38 (7.7%) | 1.39 (0.86–2.23) | 0.178 | ||
dominant | C/C | 216 (45.3%) | 248 (50.2%) | 1.00 | – | |
G/C-G/G | 261 (54.7%) | 246 (49.8%) | 1.16 (0.95–1.42) | 0.143 | ||
recessive | C/C-G/C | 429 (89.9%) | 456 (92.3%) | 1.00 | – | |
G/G | 48 (10.1%) | 38 (7.7%) | 1.18 (0.91–1.53) | 0.214 | ||
log-additive | – | – | – | 1.30 (0.82–2.05) | 0.259 | |
rs12459936 | codominant | C/C | 158 (33.5%) | 139 (28.1%) | 1.00 | – |
T/C | 238 (50.5%) | 254 (51.4%) | 0.89 (0.66–1.19) | 0.422 | ||
T/T | 75 (16.0%) | 101 (20.5%) | 0.71 (0.48–1.05) | 0.082 | ||
dominant | C/C | 158 (33.5%) | 139 (28.1%) | 1.00 | – | |
T/C-T/T | 313 (66.5%) | 355 (61.9%) | 0.85 (0.70–1.03) | 0.089 | ||
recessive | C/C-T/C | 396 (84.0%) | 393 (79.5%) | 1.00 | – | |
T/T | 75 (16.0%) | 101 (20.5%) | 0.84 (0.63–1.11) | 0.212 | ||
log-additive | – | – | – | 0.77 (0.55–1.08) | 0.123 | |
rs3093144 | codominant | C/C | 304 (64.0%) | 344 (69.5%) | 1.00 | – |
T/C | 153 (32.2%) | 140 (28.3%) | 1.18 (0.88–1.56) | 0.266 | ||
T/T | 18 (3.8%) | 11 (2.2%) | 1.95 (0.89–4.28) | 0.095 | ||
dominant | C/C | 304 (64.0%) | 344 (69.5%) | 1.00 | – | |
T/C-T/T | 171 (36.0%) | 151 (30.5%) | 1.24 (0.98–1.58) | 0.075 | ||
recessive | C/C-T/C | 457 (96.2%) | 484 (97.8%) | 1.00 | – | |
T/T | 18 (3.8%) | 11 (2.2%) | 1.23 (0.93–1.62) | 0.142 | ||
log-additive | – | – | – | 1.86 (0.85–4.05) | 0.120 | |
rs3093110 | codominant | A/A | 364 (76.3%) | 378 (76.5%) | 1.00 | – |
G/A | 105 (22.0%) | 108 (21.9%) | 1.01 (0.74–1.37) | 0.977 | ||
G/G | 8 (1.7%) | 8 (1.6%) | 1.00 (0.37–2.75) | 0.994 | ||
dominant | A/A | 304 (64.0%) | 344 (69.5%) | 1.00 | – | |
G/A-G/G | 171 (36.0%) | 151 (30.5%) | 1.00 (0.76–1.32) | 0.978 | ||
recessive | A/A-G/A | 469 (98.3%) | 486 (98.4%) | 1.00 | – | |
G/G | 8 (1.7%) | 8 (1.6%) | 1.01 (0.74–1.36) | 0.977 | ||
log-additive | – | – | – | 1.00 (0.37–2.74) | 0.996 | |