Table 3 BRCA VUS detected in the cohort
From: BRCA mutations in a cohort of Iraqi patients presenting to a tertiary referral center
Gene | Nucleotide Change | AA change | Nomenclature protein | Number of patients with mutation |
|---|---|---|---|---|
BRCA1 | c.536A > G | p.Tyr179Cys | Y179C | 2 |
c.1458 T > G | p.Phe486Leu | F486 L | ||
c.1648A > C | p.Asn550His | N550H (benign) | ||
BRCA2 | c.1075G > A | p.Glu359Lys | E359K | 1 |