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Fig. 2 | BMC Medical Genetics

Fig. 2

From: The coexistence of a novel WNK1 variant and a copy number variation causes hereditary sensory and autonomic neuropathy type IIA

Fig. 2

Quantitative real-time PCR analysis of DNA and mRNA for WNK1 gene and transcript and Western Blot analysis of WNK1 protein. The WNK1 gene dosage was normalized using GAPDH gene as control. a The DNA fold change of the WNK1 gene for the family members. b The RNA fold change of the WNK1 gene for the family members. The WNK1 transcript amount was normalized using GAPDH as housekeeping gene. c The relative WNK1 protein expression level of the family members, using Western Blot. Protein expression was normalized by the use of the housekeeping GAPDH protein level. * indicates p < 0.05 compared with wild type. The error bars refer to standard error (SE) of technical replicates

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BMC Medical Genetics

ISSN: 1471-2350

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