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Table 5 Estimated frequencies of haplotypes consisting of EREG SNPs in PTB and controls

From: Polymorphism in the EREG gene confers susceptibility to tuberculosis

Haplotype

PTB (%)a

Control (%)a

χ2

P

OR[95%CI]

CACAT

279.88 (33.0)

303.06 (25.3)

13.02

0.00031

1.43 (1.18-1.74)

CGATT

84.46 (10.0)

104.24 (8.7)

0.75

0.39

1.14 (0.85-1.54)

CGCTT

387.42 (45.7)

607.71 (50.6)

6.77

0.0093

0.79 (0.66-0.94)

TGCAG

73.76 (8.7)

101.12 (8.5)

0.011

0.92

1.017 (0.74-1.39)

  1. a Frequencies <0.03 were excluded from the analysis
  2. Global p<0.01
  3. The order of the SNPs in the haplotype is rs10518126 rs2367707 rs3806794 rs6446993 rs6836436