Table 4 Allele and genotypic frequencies of EREG SNPs in the EPTB and controls
From: Polymorphism in the EREG gene confers susceptibility to tuberculosis
SNP | Allele/genotype | EPTB (%) | HC (%) | P | OR[95%CI]a |
|---|---|---|---|---|---|
rs10518126 | C | 353 (88.2) | 1092 (91.0) | 0.11 | |
T | 47 (11.7) | 108 (9.0) | |||
C/C | 158 (79.0) | 492 (82.0) | 0.0026* | 1.08(0.71-1.64) | |
C/T | 37 (18.5) | 108 (18.0) | |||
T/T | 5 (2.5) | 0 (0.0) | |||
rs2367707 | A | 146 (36.5) | 312 (26.0) | 0.00029* | 1.64 (1.29-2.08) |
G | 254 (63.5) | 888 (74.0) | |||
A/A | 25 (12.5) | 48 (8.0) | 0.0012* | 2.22 (1.29-3.83) | |
A/G | 96 (48.0) | 216 (36.0) | |||
G/G | 79 (39.5) | 336 (56.0) | |||
rs3806794 | A | 46 (11.5) | 112 (9.3) | 0.21 | |
C | 354 (88.5) | 1088 (90.7) | |||
A/A | 7 (3.5) | 9 (1.5) | 0.21 | ||
A/C | 32 (16.0) | 94 (15.7) | |||
C/C | 161 (80.5) | 497 (82.8) | |||
rs6446993 | A | 205 (51.2) | 486 (40.5) | 0.00087* | 1.54 (1.23-1.94) |
T | 195 (48.7) | 714 (59.5) | |||
A/A | 55 (27.5) | 108 (18.0) | 0.0069* | 0.68 (0.45-1.02) | |
A/T | 95 (47.5) | 270 (45.0) | |||
T/T | 50 (25.0) | 222 (37.0) | |||
rs6836436 | G | 50 (12.5) | 126 (10.5) | 0.27 | |
T | 350 (87.5) | 1074 (89.5) | |||
G/G | 5 (2.5) | 6 (1.0) | 0.27 | ||
G/T | 40 (20.0) | 114 (19.0) | |||
T/T | 155 (77.5) | 480 (80.0) |