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Fig. 4 | BMC Medical Genetics

Fig. 4

From: Novel mutations in HSF4 cause congenital cataracts in Chinese families

Fig. 4

The structural changes of the missense mutations. a Surface change of HSF4:p.R73L. The molecular surface is colored according to electrostatic potential with Swiss-PdbViewer, with red-white-blue corresponding to acidic-neutral-basic potential. b HSF4:p.Y78C gains an H-bond with L75. c HSF4:p.S105 T gains an H-bond with P104. d HSF4:p.F63 L gains an H-bond with L59. Yellow dotted circle represents the region of significant alteration. Green dotted lines indicate potential strong H-bonds

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