Fig. 3
From: Clinical and genetic characteristics of pulmonary arterial hypertension in Lebanon
Pedigrees for the p.S775 BMPR2 mutation in three families with the second hit mutations shown in the table. Square, Male; Circle, female; open symbol, unaffected; filled symbol, affected; symbol with diagonal line, dead individual; the −/− symbol is for normal genes, −/+ is for heterozygous mutations and the +/+ is for homozygous mutations. N/A stands for non-applicable because DNA is not available