Skip to main content

Advertisement

Table 1 Summary of F12 mutations and clinical presentation of patients with venous thrombosis

From: The prevalence of heterozygous F12 mutations in Chinese population and its relevance to incidents of thrombosis

Patient ID gender Age range thrombotic events,times F12 mutation FXII:C (%) PC:A (%) FPS:Ag (%) AT:A (%) Hcy (μM) APS-Ab
1 Female 30~ 39 DVT,2 A343P 33.2 98 86 115 3.4 ND
2 Female 30~ 39 DVT,1 A343P 44.8 110 90 101 7.2 ND
3 Male 50~ 59 DVT,2 A343P 53.3 84 79 98 4.9 ND
4 Male 40~ 49 CVST,1 A343P 51.8 122 101 93 9.0 ND
5 Male 30~ 39 DVT/PE,2 A343P 56.5 105 76 109 5.7 ND
6 Male 20~ 29 PE,1 D291E 72.9 92 80 110 4.1 ND
RR 50-150 70-140 60-130 85-120 6.3-15  
  1. FXII:C, factor XII activity; PC:A, protein C activity; FPS:Ag, free protein S antigen; AT:A, antithrombin activity; Hcy, homocysteine; APS-Ab, Anti-phospholipid syndrome-associated antibodies; DVT, deep vein thrombosis; CVST, cerebral venous sinus thrombosis; PE, pulmonary embolism; ND, not detected; RR, reference range