Table 7 Most of the BRCA2 mutations variants detected within African literature

c. 2826_2829delAATT

South Africa

van der Merwe NC, et al. 2012 [57]

c. 5771_5774delTTCA

c. 6448dupTA

c. 7934delG

Founder-

c.5946delT

C.8162delG

Schoeman M, et al. 2013 [58]

c.5999del4

c.6174delT

c.582G > A

Francies FZ, et al. 2015 [59]

c.5771_5774delTTCA

c.5213_5216delCTTA

c.8754 + 1G > A

c.9097_9098insA

c.4798_4800delAAT

c.7712A > G

c.9875C > T

c.7934delG founder

founder

Afrikaner population of South Africa

Seymour HJ, et al.2016 [60]

c.6621delA

South Africa

c.6761_6762delTT

c.5073dupA

Morocco

LAARABI FZ, et al.2011 [61]

c.3381delT

Tazzite A, et al. 2012 [62]

c.7110delA

c.7235insG

c.517-1G > A

c.6428 C > A

Guaoua S, et al.2014 [63]

c.745-1G > A

Jouhadi H, et al.2016 [64]

c.5682insA

Tunisia

Troudi W, et al. 2007 [65]

c.1309del4

c.-25G > A

c.6301 A > C

c.1595 A > T

c.7242 A > G

c.865 A > G

c.1310_1313del (1538delAAGA)

Fourati A, et al. 2014 [66]

c.-26G > A

Riahi A, et al.2014 [67]

c.681 + 56C > T

c.793 + 65_793 + 65delT

C.8503 T > C

5456delGTAGCA

Hadiji-Abbes N,et al. 2015 [68]

c.1313dupT

Riahi A, et al.2015 [69]

c.7654dupT

c.67 + 62 T > G

c.8487 + 47C > T

c.8360G > A

c.8830A > T

c.9875C > T

c.10240A > G

c.8182G > A

c.8503 T > C

c.1542_1547delAAGA

Riahi A, et al. 2017 [70]

c.5682insA

c.1309del4

c.1310 1313delAAGA

Algeria

Cherbal F, et al. 2010 [71]

c.5722 5723delCT

c.67 + 14 T > C

c.67 + 15 T > C

c.68–14 T > A

c.68-21 T > G

c.231 T > G

c.3555A > T

c.3868 T > A

c.5553C > T

c.5472 T > G

c.5592C > A

c.5976A > G

c.5985C > A

c.8487 + 19A > C

c.68-16 T > A

Cherbal F, et al.2012 [72]

c.475 + 25A > G

c.794-5A > T

c.1099G > A

c.2636C > A

c.2657A > G

c.2673C > G

c.5397A > T

c.5428G > T

c.6309A > C

c.6346C > G

c.9256G > A

c.7654dupA

Henouda S, et al.2016 [73]

c.1528G > T

Del exons 19–20

c.6450del

c.7462A > G

c.1504A > C

c.5939C > T

c.1627C > A

c.3195_3198delTAAT

Sudan

Awadelkarim KD, et al.2007 [16]

c.6406_6407delTT

c.8642_8643insTTTT

c.122C > T

c.6101G > A

c.68-7delT

999TCAAA deleted (999del5)

Egypt

Bensam M, et al.2014 [74]

2256 T > C

8934G > A

c.970G > A

Nigeria

Fackenthal JD, et al.2005 [49]

c.1093A > C

c.1503A > G

c.2366 A > T

c.3014 T > C

c. 3188A > T

c. 3199A > G

c. 3492 T > C

c. 4299A > C

c. 4469C > T

c. 4791G > A

c. 5646A > G

c. 5932G > A

c. 5938C > G

c. 6741C > G

c. 7378C > A

c. 7470A > G

c. 7547A > G

c. 9058A > T

c. 9862G > C

3034delACAA

ex2-11C > T

ex7-19C > T

ex11-43 T > C

ex12-200insC

ex17-40A > G

ex18 + 109G > A

ex21-36C > G

ex22-70C > T

ex26 + 106delT

1538delAAGA c.1310_1313delAAGA

Zhang J, et al.2012 [75]

1222delA

Fackenthal JD, et al.2012 [76]

2630del11

3036delACAA

4157delC

5358delTGTA

5369delATTT

5469insTA

5581delAC

7482delAG

9045delGAAA

Q3066X