Table 2 Hydrophobic region mutations identified in this cohort by Kyte-Doolittle scale mean hydrophobicity profile analysis using BioEdit software
Hydrophobic region | No. of cases with in-frame mutation (n = 48) |
|---|---|
Not involved | 33 |
Involved | 15 |
Region I | 7 |
Region II | 1 |
Region III | 7 |
Region IV | 0 |