Table 2 Association of SNPs with DHF
From: Association of BAK1 single nucleotide polymorphism with a risk for dengue hemorrhagic fever
SNP ID (gene) | Genotype (Allele) | Patients with dengue | Chi-square test | Logistic regression analysis | |||
|---|---|---|---|---|---|---|---|
DHF | DF | Crude OR (95 % CI) | P-value | Adjusted OR (95 % CI) | P-value | ||
rs5745568 (BAK1) | TT | 48 | 47 | ||||
GT | 191 | 187 | |||||
GG | 265 | 173 | |||||
G-allele | 721 (71.5 %) | 533 (65.5 %) | 1.32 (1.09–1.60) | 0.006 | 1.29 (1.05–1.58) | 0.016 | |
rs6141 (THPO) | TT | 82 | 70 | ||||
CT | 260 | 189 | |||||
CC | 164 | 148 | |||||
C-allele | 588 (58.1 %) | 485 (59.6 %) | 0.94 (0.78–1.14) | 0.520 | 0.98 (0.80–1.19) | 0.844 | |
rs6065 (GP1BA) | TT | 2 | 0 | ||||
CT | 37 | 42 | |||||
CC | 467 | 366 | |||||
C-allele | 971 (96.0 %) | 774 (94.9 %) | 1.29 (0.83–2.00) | 0.263 | 1.35 (0.85–2.14) | 0.203 | |
rs739496 (SH2B3) | AA | 18 | 12 | ||||
AG | 137 | 114 | |||||
GG | 350 | 281 | |||||
A-allele | 173 (17.1 %) | 138 (17.0 %) | 1.01 (0.79–1.29) | 0.921 | 0.96 (0.74–1.24) | 0.731 | |
rs385893 (RCL1) | TT | 49 | 39 | ||||
CT | 200 | 165 | |||||
CC | 258 | 205 | |||||
T-allele | 298 (29.4 %) | 243 (29.7 %) | 0.98 (0.80–1.21) | 0.882 | 1.02 (0.83–1.25) | 0.886 | |
rs4804803 (CD209) | AA | 411 | 323 | ||||
GA | 92 | 77 | |||||
GG | 4 | 8 | |||||
G-allele | 100 (9.8 %) | 93 (11.4 %) | 0.85 (0.63–1.15) | 0.288 | 0.83 (0.61–1.13) | 0.242 | |