Fig. 1
From: Osteoblastic differentiation of bone marrow mesenchymal stromal cells in Bruck Syndrome
Adipogenic and Osteogenic differentiation of mesenchymal stem cells (MSCs) after passage 3. a. BS patient; not induced MSC; undifferentiated, magnitude order: 630X. b. BS cells differentiated into adipocyte after staining with Sudan II-Scarlat assay, magnitude order: 630X c. BS cells differentiated in osteoblast after staining with Von Kossa assay; magnitude order: 10X. d normal donor; not induced MSC; magnitude order: 100X. e. Normal donor cells differentiated into adipocyte, magnitude order: 630X. Sudan II staining showed MSC adipogenic differentiation after 10 days. f. normal donor cells differentiated in osteoblast; magnitude order: 10X. g. OI patient, undifferentiated MSC; magnitude order: : 630X. h. OI patient cells differentiated into adipocyte; magnitude order: 630X i. OI patients’ cells differentiated in osteoblast; magnitude order: 10X. Von Kossa staining showed mineralization nodules (black) and MSCs morphology changed from spindle to cuboid shape after 14 days