Fig. 1From: Next-generation-based targeted sequencing as an efficient tool for the study of the genetic background in Hirschsprung patientsFamily trees of patients 2, 3, 5 and 8. All previously identified variants and the new ones found in this study were included. Symbols: V = variant; arrow = patient included in the study; genotypes: − = wildtype allele; + = non-standard allele; * = not available DNABack to article page