Table 2 Frequencies of the C4B null allele and CYP21A2 mutations
From: C4B null alleles are not associated with genetic polymorphisms in the adjacent gene CYP21A2in autism
| Â | Autism | Control | P-value |
|---|---|---|---|
C4B null allele | 40/160 | 10/120 | P = 0.0003 |
30 kb deletion/conversion | 1/160 | 2/120 | Not significant (NS) |
CYP21A2 mutations | Â | Â | Â |
   V281L | 3/160 | 1/120 | NS |
   I172N | 1/160 | 2/120 | NS |
   R356W | 1/160 | 0/120 | NS |
   P30L | 2/160 | 1/120 | NS |
   IN2 | 0/160 | 0/120 | NS |
   Ex 3 Del | 0/160 | 1/120 | NS |
   Ex 6 cluster | 0/160 | 0/120 | NS |