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Table 1 Baseline characteristics of low HDL-C and control subjects

From: Sphingomyelin phosphodiesterase-1 (SMPD1) coding variants do not contribute to low levels of high-density lipoprotein cholesterol

 

Control subjects (n = 230)

Low HDL-C subjects (n = 118)

t test p*

Age (y)

50 ± 9

50 ± 10

0.93

Gender (M/F)

150/80

85/33

0.20

BMI (kg/m2)

26.3 ± 4.5

28.1 ± 4.9

0.001

DM (%)

10.4

21.2

0.01

HTN (%)

20.4

45.8

<0.001

CAD (%)

49.8

72.3

<0.001

FH of CAD (%)

61.3

72.6

0.04

TG (mmol/L)

1.63 ± 0.89

3.95 ± 3.35

<0.001

T Chol (mmol/L)

5.73 ± 1.41

5.98 ± 2.20

0.26

HDL-C (mmol/L)

1.35 ± 0.33

0.67 ± 0.13

<0.001

LDL-C (mmol/L)

3.70 ± 1.33

3.50 ± 1.61

0.27

  1. BMI, body mass index; DM, diabetes mellitus; HTN, hypertension; CAD, coronary artery disease; FH, familial history; TG, plasma triglycerides; T Chol, total plasma cholesterol; HDL-C, plasma high-density lipoprotein cholesterol; LDL-C, plasma low-density cholesterol.
  2. * significant p-value bolded.
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BMC Medical Genetics

ISSN: 1471-2350

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