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Figure 2 | BMC Medical Genetics

Figure 2

From: Lack of increases in methylation at three CpG-rich genomic loci in non-mitotic adult tissues during aging

Figure 2

Epigenetic molecular clocks or tags. A: Sequences (after bisulfite conversion) of the CSX (8 CpG sites), BGN (9 CpG sites), and SOX10 (20 CpG sites) tags. Primer sites are underlined, CpG sites are in bold, and a bisulfite converted "C" at a non-CpG site is indicated by "T". B: Examples of CSX and SOX10 tags sampled from the heart, brain, liver or kidney of different aged individuals. The tags are arranged in a 5' to 3' horizontal order with methylated sites indicated by filled circles. There are eight alleles per tissue. Patient H did not have a liver specimen and the liver is instead from Patient G, a 31 year old.

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BMC Medical Genetics

ISSN: 1471-2350

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