Figure 3

At the top of the figure: Electropherogram of amplicon b of the ARX exon 2 in MRX87 IV:14. The box indicates the nucleotide sequence duplicated in the ARX gene (c.428_451dup24 also known as ARXdup24). At the bottom of the figure: ARX protein functional domains and polyA tracts are shown, next to the various mutations that results in a spectrum of developmental brain phenotypes. *[10], #[13], °[14], ^[19], §[27], ∑[30], ≠[31], $[32], &[33].