Figure 1

Distribution of high-risk (dark shading) and low-risk (light shading) combinations associated with atrial fibrillation in the four significant gene-environment models using Multifactor Dimensionality Reduction (MDR) analysis. The percentage of patients with atrial fibrillation (left bar in boxes) and matched control subjects (right bar in boxes) is shown for each combination. Boxes were labeled as high-risk (dark-shaded) if the ratio of the percentage of cases to controls met or exceeded the threshold of 1.0.