Three novel and the common Arg677Ter RP1 protein truncating mutations causing autosomal dominant retinitis pigmentosa in a Spanish population

Table 4 ERG values of Spanish families with RP1 mutations

		RODS		MIXED (ROD-CONES)				CONOS		30 Hz Flicker
INDIVIDUAL	EYE	b-wave AMPL.	b-wave IMP.T	a-wave AMPL	a-wave IMP.T.	b-wave AMPL.	b-wave IMP.T	b-wave AMP.	b-wave IMP.T	b-wave AMPL	b-wave IMP.T
Q686X
I-1	R	ND	ND	ND	ND	ND	ND	50	36	NV	NV
	L	ND	ND	ND	ND	ND	ND	30	37	NV	NV
II-1	R	260	109	378	23	874	49	218	30	131	29
	L	230	105	363	23	833	48	238	31	144	29
II-6	R	ND	ND	ND	ND	ND	ND	ND	ND	ND	ND
	L	ND	ND	ND	ND	ND	ND	ND	ND	ND	ND
III-6	R	110	93	158	22	389	44	142	31	97	27
	L	157	108	213	22	441	44	140	31	65	25
III-7	R	116	99	197	22	491	45	154	30	68	27
	L	137	94	170	22	412	45	NV	NV	NV	NV
K705fsX712
II-1	R	ND	ND	39	24	267	49	85	34	38	32
	L	ND	ND	51	26	246	52	76	35	63	33
III-1	R	-	-	-	-	-	-	-	-	-	-
	L	-	-	-	-	-	-	-	-	-	-
III-3	R	ND	ND	ND	ND	ND	ND	ND	ND	ND	ND
	L	ND	ND	ND	ND	ND	ND	ND	ND	ND	ND
III-4	R	177	93	198	21	492	51	198	29	148	27
	L	187	93	199	21	527	49	230	30	122	27
III-5	R	186	104	221	22	556	47	166	30	58	28
	L	209	109	219	21	500	47	168	30	75	28
III-6	R	-	-	-	-	-	-	-	-	-	-
	L	-	-	-	-	-	-	-	-	-	-
III-11	R	165	103	274	22	500	46	101	32	77	30
	L	169	106	299	23	563	46	104	31	83	29
III-12	R	-	-	-	-	-	-	-	-	-	-
	L	-	-	-	-	-	-	-	-	-	-
III-14	R	170	100	266	21	705	49	207	29	127	29
	L	166	103	195	21	570	48	204	29	100	29
IV-1	R	106	86	150	21	393	45	152	29	64	26
	L	138	91	191	21	491	46	193	29	80	27
K722fsX737
I-1	R	-	-	-	-	-	-	-	-	-	-
	L	-	-	-	-	-	-	-	-	-	-
II-2, II-3, II-4	R	ND	ND	ND	ND	ND	ND	ND	ND	ND	ND
	L	ND	ND	ND	ND	ND	ND	ND	ND	ND	ND

ISSN: 1471-2350