Cell cycle and centromere FISH studies in premature centromere division

BMC Medical Genetics

Table 3 Main features of published families with PCD and present report.

FEATURES	Rudd et al. 1983 [6]			Gabarrón et al. 1986 [7]	Madan et al. 1987 [8]	Bajnoczky and Gardó 1993 [9]	Keser et al. 1996 [10]			Present report
	A	B	C				A	B	C
Individuals with PCD	3	4	3	4	4	4	4	3	1	4
Individuals with abortion or infertility	2/3^§§	0	1/3^§	2/4^§	0	2/4^§	1/4^§	2/4^§	1/1^§	1/4^§§
PCD in colchicine treated cultures *	14–15	17–62	10–16	5.2–36	6–12	7–38	6–21	6–28	32	5–55
PCD in untreated cultures *	7–20	10–21	6–6.5	8.5–39	0–3	NI	17	7	NI	5
Controls *	0–0.5	0–0.5	0–0.5	1	0–1	4.1–5.2	0–1	0	0	0.87
Cd stain	NI**	NI	NI	NI	+	NI	NI	NI	NI	+
Cell cycle	Short	NI	NI	Short	NI	NI	NI	NI	NI	Short

* = range of percentages. ** = Non investigated. ^§ = Individuals with abortion. ^§§ = Individuals with infertility.

ISSN: 1471-2350