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Table 2 Genotype and allele frequencies of SNP rs759330 in BGLAP gene

From: A whole genome SNP genotyping by DNA microarray and candidate gene association study for kidney stone disease

Genotype

Genotype frequency (%)

OR (95% CI)

P-value (Corrected)

Allele

Allele frequency (%)

OR (95% CI)

P-value (Corrected)

Control

Patient

Control

Patient

SNP array

(n = 105)

(n = 101)

   

(n = 105)

(n = 101)

  

T/T

75.2

55.5

1.00

0.0027 (4.2093)

T

87.1

74.3

1.00

0.0009 (1.4031)

T/C, C/C

24.8

44.5

2.44 (1.35-4.41)

C

12.9

25.7

2.35 (1.41-3.92)

HRM

(n = 216)

(n = 216)

   

(n = 216)

(n = 216)

  

T/T

75.0

59.7

1.00

0.0007 (0.0035)

T

87.0

76.9

1.00

0.0001 (0.0005)

T/C, C/C

25.0

40.3

2.02 (1.34-3.05)

C

13.0

23.1

2.02 (1.41-2.90)

  1. OR, odds ratio; CI, confidence interval.
  2. Corrected P-values are adjusted for multiple comparisons (1,559 tests for SNP array and 5 tests for HRM method). Statistical significance cut off values are P = 0.00032 and P = 0.01 for the analyses by SNP array and HRM, respectively.
  3. Significant P-values are indicated in bold.