SNP | 1/2 | Subgroup (n) | 11 | 12 | 22 | MAF (%) | Allelic P-value | OR (95% CI) |
---|---|---|---|---|---|---|---|---|
IL2/IL21 | ||||||||
rs2069762 | C/A | Controls (n=760) | 61 (8.03) | 315 (41.45) | 384 (50.53) | 437 (28.75) | ||
Uveitis (n=195) | 17 (8.71) | 85 (43.60) | 93 (47.69) | 119 (30.51) | 0.49 | 1.09 (0.85-1.40) | ||
rs6822844 | T/G | Controls (n=760) | 15 (1.97) | 156 (20.53) | 589 (77.50) | 186 (12.24) | ||
Uveitis (n=196) | 2 (1.02) | 28 (14.29) | 166 (84.69) | 32 (8.16) | 0.02* | 0.64 (0.43-0.94) | ||
rs907715 | T/C | Controls (n=760) | 81 (10.66) | 330(43.42) | 349(46.92) | 492 (32.37) | ||
Uveitis (n=196) | 26 (13.27) | 70 (35.71) | 100 (51.02) | 122 (31.12) | 0.64 | 0.94 (0.74-1.20) | ||
IL2RA | ||||||||
rs12722495 | G/A | Controls (n=760) | 3 (0.39) | 114 (15.00) | 643 (84.61) | 120 (7.90) | ||
Uveitis (n=196) | 2 (1.02) | 29 (14.80) | 165 (84.18) | 33 (8.42) | 0.73 | 1.07 (0.72-1.60) | ||
rs2104286 | C/T | Controls (n=760) | 19 (2.50) | 270 (35.53) | 471 (61.97) | 308 (20.26) | ||
Uveitis (n=196) | 10 (5.10) | 60(30.61) | 126 (64.29) | 80 (20.41) | 0.95 | 1.01 (0.77-1.33) | ||
rs11594656 | T/A | Controls (n=760) | 84 (11.05) | 346(45.53) | 330(43.42) | 514 (33.82) | ||
Uveitis (n=196) | 23 (11.79) | 69 (35.38) | 103 (52.82) | 115 (29.49) | 0.10 | 0.82 (0.64-1.04) | ||
IL2RB | ||||||||
rs743777 | G/A | Controls (n=760) | 86(11.32) | 349(45.92) | 325(42.76) | 521 (34.28) | ||
Uveitis (n=195) | 26 (13.40) | 72 (37.11) | 96 (49.48) | 124 (31.96) | 0.39 | 0.90 (0.71-1.14) |