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Table 1 Baseline clinical, metabolic, and demographic characteristics of each cohort by gender

From: A comprehensive investigation of variants in genes encoding adiponectin (ADIPOQ) and its receptors (ADIPOR1/R2), and their association with serum adiponectin, type 2 diabetes, insulin resistance and the metabolic syndrome

 

BHS

CUDAS

FDS

 

Female (n=736)

Male (n=586)

Female (n=521)

Male (n=512)

Female (n=489)

Male (n=478)

Adiponectin (mg/L)

14.2 (8.1–24.8)

7.9 (4.2–15.0)

13.9 (8.1–23.8)

7.9 (4.5–14.0)

8.6 (4.4–16.6)

5.9 (3.0–11.4)

Age (years)

51.3±17.8

51.5±17.7

52.8±12.7

53.2±12.8

64.6±11.4

64.4±10.3

SBP (mm Hg)

122±20

126±16

126±20

129±16

150±23

151±23

DBP (mm Hg)

73±10

77±10

78±11

82±9

79±11

83±11

Fasting Glucose (mmol/L)

4.8±0.5

4.9±0.5

5.3±0.7

5.3±0.8

8.7 (6.3–12.0)

8.6 (6.2–11.8)

Fasting Insulin (IU/L)*

41.6 (24.6–70.3)

44.6 (24.6–80.8)

33.6 (18.4–61.4)

36.1 (19.1–68.5)

80.7 (44.2–147.2)

68.0 (34.6–133.4)

lnHOMA-IR (insulin resistance)

0.9 (0.5–1.5)

0.9 (0.5–1.7)

0.6 (0.3–1.2)

0.7 (0.4–1.3)

1.7 (0.9–3.2)

1.4 (0.7–2.8)

Total cholesterol (mmol/L)

5.6±1.2

5.5±1.0

5.6±1.0

5.5±1.0

5.7±1.1

5.2±1.1

LDL-cholesterol (mmol/L)

3.5±1.0

3.7±0.9

3.6±0.9

3.7±0.9

3.6±1.0

3.3±0.8

HDL-cholesterol (mmol/L)

1.51 (1.17–1.95)

1.18 (0.91–1.54)

1.47 (1.14–1.88)

1.14 (0.89–1.47)

1.09 (0.82–1.46)

0.93 (0.68–1.26)

Serum triglycerides (mmol/L)

1.0 (0.6–1.7)

1.2 (0.7–2.2)

1.0 (0.6–1.6)

1.2 (0.7–2.1)

1.9 (1.2–3.0)

1.9 (1.0–3.4)

Body Mass Index (BMI) (kg/m2)

25.1±4.4

26.3±3.5

25.3±4.4

26.6±3.5

30.2±5.9

28.9±4.5

Waist circumference (cm)

79.7±11.0

92.9±10.2

76.9±10.4

92.0±9.2

96.4±12.6

103.4±11.2

Waist-Hip ratio

0.79±0.06

0.93±0.06

0.76±0.06

0.90±0.05

0.86±0.06

0.96±0.06

Antihypertensive tx (%)

19.2

16.1

13.8

13.9

56.4

45.4

Smoking (never/ex/current) (%)

60.2/28.9/10.9

47.6/37.1/15.2

62.8/24.2/13.1

39.1/43.6/17.4

64.4/23.6/12.0

24.9/57.4/17.6

NCEP_Hypertension (%)

40.0

46.2

47.0

54.7

92.8

91.0

NCEP_Hyperglycaemia (%)

7.1

10.0

33.9

40.2

94.3

93.5

NCEP_Hypertriglyceridemia (%)

17.4

28.9

14.8

30.7

59.0

58.7

NCEP_LowHDL (%)

27.3

26.8

30.1

29.3

73.1

60.0

NCEP_Obese (%)

20.7

18.1

16.3

14.8

74.1

55.0

NCEP_MetSScore† (%)

      

0

39.8

31.7

27.2

18.6

0.4

0.2

1

29.9

32.3

29.5

27.1

1.0

2.0

2

16.6

18.3

26.4

29.6

8.5

15.8

3+

13.7

17.7

17.0

24.7

90.0

82.0

  1. * insulin in non-insulin users † NCEP_MetSScore is the number of MetS components.
  2. The data for continuous variables is mean±standard deviation, or geometic mean (standard deviation range). The data for categorical variables is shown as proportions.
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BMC Medical Genetics

ISSN: 1471-2350

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