From: Toll-like receptor gene polymorphisms are associated with allergic rhinitis: a case control study
Association test | Skin prick test | ||||||||||
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Gene | SNP ID | Position* | Alleles | MAF† | HW | Allele M + F | Allele M | Allele F | Genotype | B. tp ‡ | D. pt # |
TLR7 | rs179021 | 12889763 | T/G | 0.01 | 1.0 | 0.72 | 0.42 | 0.62 | 0.62 | 0.70 | 0.12 |
TLR7 | rs179020 | 12889857 | G/A | 0.25 | 0.26 | 0.65 | 0.38 | 0.36 | 0.56 | 0.021 (0.32) | 0.010 (0.025) |
TLR7 | rs179019 | 12889969 | C/A | 0.25 | 0.34 | 0.78 | 0.36 | 0.44 | 0.70 | 0.022 (0.32) | 0.0090 (0.025) |
TLR7 | rs179016 | 12894442 | G/C | 0.12 | 1.0 | 0.61 | 0.62 | 0.81 | 0.85 | 0.094 | 0.013 (0.025) |
TLR7 | rs179014 | 12899765 | G/A | 0.00 | 1.0 | 0.80 | - | 0.91 | 0.91 | 0.091 | 0.24 |
TLR7 | rs179013 | 12901471 | G/A | 0.01 | 1.0 | 0.85 | 0.42 | 0.76 | 0.76 | 0.72 | 0.14 |
TLR7 | rs179012 | 12901562 | G/A | 0.06 | 1.0 | 0.66 | 0.92 | 0.75 | 0.95 | 0.67 | 0.011 (0.025) |
TLR7 | rs179011 | 12901960 | G/T | 0.01 | 1.0 | 0.65 | 0.42 | 0.58 | 0.58 | 0.73 | 0.13 |
TLR7 | rs179010 | 12902885 | C/T | 0.35 | 0.18 | 0.86 | 0.45 | 0.52 | 0.59 | 0.078 | 0.0046 (0.025) |
TLR7 | rs179008 | 12903659 | A/T | 0.00 | 1.0 | 0.37 | - | 0.47 | 0.47 | 0.76 | 0.43 |
TLR7 | rs864058 | 12906030 | G/A | 0.00 | 0.0091 | 0.92 | 0.57 | 0.85 | 0.39 | 0.28 | 0.88 |
TLR7 | rs179007 | 12910322 | A/G | 0.00 | 0.0044 | 0.17 | - | 0.25 | 0.55 | 0.76 | 0.43 |
TLR7 | rs179006 | 12910521 | G/A | 0.00 | 0.0036 | 0.17 | - | 0.25 | 0.55 | 0.76 | 0.43 |
TLR7 | rs2269809 | 12910619 | T/G | 0.16 | 0.20 | 0.38 | 0.061 | 0.97 | 0.27 | 0.59 | 0.18 |
TLR7 | rs5935438 | 12913022 | G/C | 0.15 | 0.017 | 0.34 | 0.056 | 0.92 | 0.27 | 0.77 | 0.26 |
TLR8 | rs178998 | 12917787 | T/C | 0.16 | 0.053 | 0.18 | 0.024 (0.072) | 0.74 | 0.34 | 0.43 | 0.56 |
TLR8 | rs3788935 | 12922659 | G/A | 0.17 | 0.10 | 0.27 | 0.025 (0.072) | 0.85 | 0.80 | 0.45 | 0.14 |
TLR8 | rs5741883 | 12924221 | C/T | 0.02 | 0.35 | 0.66 | 0.84 | 0.64 | 0.39 | 0.27 | 0.53 |
TLR8 | rs17256081 | 12926045 | T/C | 0.15 | 0.018 | 0.20 | 0.010 (0.072) | 0.86 | 0.54 | 0.84 | 0.19 |
TLR8 | rs4830805 | 12927759 | A/G | 0.19 | 0.29 | 0.42 | 0.016 (0.072) | 0.84 | 0.74 | 0.40 | 0.053 |
TLR8 | rs1548731 | 12927947 | C/T | 0.02 | 0.68 | 0.33 | 0.93 | 0.38 | 0.26 | 0.16 | 0.25 |
TLR8 | rs4830808 | 12932334 | T/C | 0.23 | 0.41 | 0.16 | 0.054 | 0.58 | 0.85 | 0.091 | 0.057 |
TLR8 | rs2407992 | 12939112 | C/G | 0.19 | 0.18 | 0.023 (0.33) | 0.0054 (0.072) | 0.30 | 0.59 | 0.12 | 0.45 |