From: Toll-like receptor gene polymorphisms are associated with allergic rhinitis: a case control study
Association test | Skin prick test | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Gene | SNP ID | Position* | Alleles | MAF† | HW | Allele M + F | Allele M | Allele F | Genotype | Birch | Timothy grass |
TLR7 | rs179021 | 12889763 | T/G | 0.22 | 0.25 | 0.60 | 0.54 | 0.82 | 0.50 | 0.64 | 0.061 |
TLR7 | rs179020 | 12889857 | G/A | 0.24 | 0.32 | 0.40 | 0.71 | 0.16 | 0.36 | 0.17 | 0.49 |
TLR7 | rs179019 | 12889969 | C/A | 0.24 | 0.32 | 0.41 | 0.69 | 0.16 | 0.36 | 0.17 | 0.49 |
TLR7 | rs179016 | 12894442 | G/C | 0.36 | 0.52 | 0.34 | 0.31 | 0.69 | 0.61 | 0.90 | 0.14 |
TLR7 | rs179014 | 12899765 | G/A | 0.24 | 0.13 | 0.58 | 0.65 | 0.25 | 0.45 | 0.19 | 0.43 |
TLR7 | rs179013 | 12901471 | G/A | 0.22 | 0.44 | 0.42 | 0.50 | 0.56 | 0.63 | 0.42 | 0.095 |
TLR7 | rs179012 | 12901562 | G/A | 0.29 | 0.98 | 0.67 | 0.68 | 0.84 | 0.83 | 0.32 | 0.28 |
TLR7 | rs179011 | 12901960 | G/T | 0.23 | 0.20 | 0.41 | 0.63 | 0.44 | 0.57 | 0.46 | 0.093 |
TLR7 | rs179010 | 12902885 | C/T | 0.31 | 0.012 | 0.47 | 0.95 | 0.26 | 0.55 | 0.97 | 0.90 |
TLR7 | rs179008 | 12903659 | A/T | 0.22 | 0.16 | 0.29 | 0.38 | 0.47 | 0.44 | 0.39 | 0.11 |
TLR7 | rs864058 | 12906030 | G/A | 0.07 | 0.80 | 0.37 | 0.29 | 0.65 | 0.56 | 0.44 | 0.44 |
TLR7 | rs179007 | 12910322 | A/G | 0.23 | 0.81 | 0.53 | 0.50 | 0.90 | 0.87 | 0.20 | 0.21 |
TLR7 | rs179006 | 12910521 | G/A | 0.20 | 0.61 | 0.17 | 0.46 | 0.30 | 0.43 | 0.42 | 0.22 |
TLR7 | rs2269809 | 12910619 | G/T | 0.50 | 0.057 | 0.58 | 0.91 | 0.40 | 0.028 (0.064) | 0.81 | 0.054 |
TLR7 | rs5935438 | 12913022 | G/C | 0.45 | 0.21 | 0.28 | 0.99 | 0.22 | 0.0059 (0.064) | 0.81 | 0.019 (0.051) |
TLR8 | rs178998 | 12917787 | C/T | 0.34 | 0.045 | 0.19 | 0.86 | 0.080 | 0.15 | 0.10 | 0.23 |
TLR8 | rs3788935 | 12922659 | A/G | 0.23 | 0.53 | 0.0036 (0.076) | 0.36 | 0.0037 (0.046) | 0.012 (0.064) | 0.44 | 0.23 |
TLR8 | rs3761624 | 12923681 | A/G | 0.22 | 0.62 | 0.0080 (0.076) | 0.49 | 0.0056 (0.046) | 0.016 (0.064) | 0.40 | 0.16 |
TLR8 | rs5741883 | 12924221 | C/T | 0.25 | 0.96 | 0.28 | 0.96 | 0.17 | 0.068 | 0.67 | 0.038 (0.054) |
TLR8 | rs17256081 | 12926045 | T/C | 0.49 | 0.11 | 0.80 | 0.64 | 0.98 | 0.021 (0.064) | 0.76 | 0.0066 (0.035) |
TLR8 | rs4830805 | 12927759 | G/A | 0.21 | 0.92 | 0.0069 (0.076) | 0.25 | 0.013 (0.071) | 0.042 (0.064) | 0.34 | 0.080 |
TLR8 | rs1548731 | 12927947 | C/T | 0.27 | 0.93 | 0.50 | 0.89 | 0.48 | 0.046 (0.064) | 0.94 | 0.49 |
TLR8 | rs4830808 | 12932334 | C/T | 0.16 | 0.44 | 0.70 | 0.53 | 0.38 | 0.55 | 0.24 | 0.22 |
TLR8 | rs2407992 | 12939112 | G/C | 0.38 | 0.068 | 0.63 | 0.75 | 0.40 | 0.67 | 0.42 | 0.040 (0.054) |