SNP | Gene | Inheritance model | Genotypes | OR (95% CI)a
| p-valuea
|
---|
rs1801275
|
IL4R
| Overdominant | A/A-G/G | 1.00 | |
| | | A/G | 0.66 (0.46-0.95) |
0.025
|
rs301640
|
STAT4 binding site
| Log-additive | A | 1.82 (1.17-2.83) |
0.0064
|
rs4586
|
CCL2
| Log-additive | C | 0.70 (0.54-0.90) |
0.0051
|
rs7830
|
NOS3
| Log-additive | T | 1.31 (1.01-1.71) |
0.043
|
- Abbreviations: ESRD, end-stage renal disease; IL4R, interleukin 4 receptor; STAT4 signal transducer and activator of transcription 4; CCL2, chemokine (C-C motif) ligand 2; NOS3 nitric oxide synthase 3; OR, odds ratio; 95%CI, 95% confidence interval; p-value, level of significance.
-
aOR and p-value of adjusted model by age and gender.