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Table 6 Association of the main PROCR haplotypes with sEPCR (log) levels in the AtheroGene study (n = 891)

From: Association of soluble endothelial protein C receptor plasma levels and PROCR rs867186 with cardiovascular risk factors and cardiovascular events in coronary artery disease patients: The Athero Gene Study

Polymorphisms

Haplotype Frequencies

Haplotypic Effects*

rs6088738

rs6088747

rs2069940

rs867186

rs1415774

Ā Ā 

G

T

G

G

G

0.108

+0.786 [0.742 - 0.829] p = 6.74 10-270

G

T

C

A

G

0.239

āˆ’0.027 [āˆ’0.061 - 0.007] p = 0.125

G

G

C

A

A

0.416

reference

A

T

C

A

G

0.228

0.028 [āˆ’0.009 - 0.066]p = 0.143

Global test for haplotypic association

Ļ‡2 with 3 df = 792.6 p =1.71 10-171

  1. * Additive effects of each inferred haplotype compared to the most frequent one used as the reference haplotype. Effects were adjusted for age, sex, smoking and CV events.
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BMC Medical Genetics

ISSN: 1471-2350

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