Gene | rs# | Nominal P | Effectc
| Chr | Coded allele | Coded allele frequency | Genetic Modelg
| Typeh
|
---|
MTHFR
| rs12121543 | 4.29E-03 | 0.48 | 1 |
A
| 24% | R | I |
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aModel adjusted for age, smoking, and residuals of plasma folate, plasma vitamin B-6, and plasma vitamin B-12; forward strand allele shown.
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bNo FDR-adjusted P values reached False Discovery Rate significance threshold of 0.05.
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cEffect represents per genotype change in LINE-1 element methylation standard deviation.
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dNo sparse data (fewer than 5 individuals per category) for any genotype categories of these SNPs.
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eNo SNPs map to more than one gene.
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fNo lower quality SNPs.
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gD:Dominant; R:Recessive; A:Additive; O:Overdominant.
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h5':5' region; 3':3' region; CN:Coding nonsynonymous; CS:Coding synonymous; I:Intronic.