Table 3 Characteristics of patients by MTHFD1L genotype (N = 3095).
Outcome | GG (n = 1366) | AG (n = 1327) | AA (n = 402) | PValue | |
|---|---|---|---|---|---|
Patient Died | 395 (12.8%) | 137 (10.0%) | 182 (13.7%) | 76 (18.9%) | < 0.001 |
Time (Year) | 0.120 | ||||
Mean ± SD | 2.8 ± 1.2 | 2.8 ± 1.1 | 2.7 ± 1.2 | 2.8 ± 1.4 | |
Median (IQR*) | 2.7 (2.0, 3.6) | 2.8 (2.1, 3.7) | 2.6 (2.0, 3.6) | 2.8 (1.8, 3.6) | |
Demographics and History | |||||
Age | 59.3 ± 12.5 | 59.9 ± 12.2 | 59.1 ± 12.8 | 57.9 ± 12.4 | 0.010 |
Sex | 0.003 | ||||
Male | 2095 (67.7%) | 944 (69.1%) | 909 (68.5%) | 242 (60.2%) | |
Female | 1000 (32.3%) | 422 (30.9%) | 418 (31.5%) | 160 (39.8%) | |
Race Category | < 0.001 | ||||
White/Caucasian | 2315 (74.9%) | 1189 (87.3%) | 943 (71.1%) | 183 (45.6%) | |
Black/African American | 607 (19.7%) | 109 (8.0%) | 303 (22.9%) | 195 (48.6%) | |
Other | 167 (5.4%) | 64 (4.7%) | 80 (6.0%) | 23 (5.7%) | |
Unknown | 6 | 4 | 1 | 1 |