Common polymorphisms of calpain-10 and the risk of Type 2 Diabetes in a Tunisian Arab population: a case-control study

Table 5 CAPN10 Haplotype Analysis

Haplotype¹	Patients	Controls	P	Pc ³	OR (95% CI)
111⁴	0.392 (719) ²	0.345 (516) ²	0.006	0.034	1.22 (1.06 - 1.41)
112	0.072 (132)	0.059 (88)	0.147	0.615	1.24 (0.94 - 1.64)
121	0.368 (675)	0.399 (597)	0.072	0.361	0.88 (0.76 - 1.01)
122	0.080 (147)	0.096 (144)	0.115	0.520	0.82 (0.64 - 1.04)
221	0.078 (143)	0.086 (129)	0.422	0.963	0.90 (0.70 - 1.15)
222	0.010 (18)	0.015 (22)	0.259	0.834	0.66 (0.36 - 1.24)

1. Haplotype frequency determined by the maximum likelihood method.
2. Haplotype frequency (number of haplotypes).
3. Pc = corrected P, calculated as per the Bonferroni method [Pc = 1 - (1 - P)ⁿ)], where n = number of comparisons.
4. CAPN10 haplotypes were coded as per the allele at each locus (wild-type = 1, mutant = 2); the first refers to UCSNP-43, the second to UCSNP-19, and the third to UCSNP-63.

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