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Table 3 Regression Analysis on T2D Risk Associated with CAPN10 Polymorphisms 1

From: Common polymorphisms of calpain-10 and the risk of Type 2 Diabetes in a Tunisian Arab population: a case-control study

  

Univariate

Multivariate

SNP

Genotype

P

OR (95% CI)

P

aOR 2(95% CI)

UCSNP-43

G/G

0.647

1.00 (Reference) 3

0.809

1.00 (Reference) 3

 

G/A

0.573

1.52 (0.35 - 6.53)

0.827

1.20 (0.24 - 6.12)

 

A/A

0.492

1.66 (0.39 - 7.03)

0.708

1.36 (0.27 - 6.85)

UCSNP-19

3R/3R

0.003

1.00 (Reference) 3

0.084

1.00 (Reference) 3

 

3R/2R

0.008

1.35 (1.08 - 1.68)

0.923

1.02 (0.66 - 1.58)

 

2R/2R

0.002

1.61 (1.20 - 2.18)

0.044

1.40 (1.01 - 1.93)

UCSNP-63

C/C

0.714

1.00 (Reference) 3

0.704

1.00 (Reference) 3

 

C/T

0.463

1.29 (0.66 - 2.52)

0.722

1.19 (0.45 - 3.17)

 

T/T

0.417

1.31 (0.68 - 2.54)

0.920

1.05 (0.39 - 2.85)

  1. 1. Study subjects comprised 917 cases and 748 age-, gender-, and origin-matched controls subjects.
  2. 2. aOR = adjusted OR; covariates included age, gender, BMI, hypertension, and lipid profile.
  3. 3. Reference group being minor allele non-carriers.
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BMC Medical Genetics

ISSN: 1471-2350

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