Table 2 The Genotype and Allelic Frequency of TLR-9 Stratified by Sex among Graves' Disease Patients in Taiwan
| Â | Â | rs187084 | Â | rs352140 | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
|  | SNP ID | with GO | w/o GO | P-value* | OR†(95% CI) |  | with GO | w/o GO | P-value* | OR†(95% CI) |
| Â | Â | N (%) | N (%) | Â | Â | Â | N (%) | N (%) | Â | Â |
Genotype | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Female | A/A | 67 (44.97) | 89 (39.91) | Â | 1 | A/A | 12 (8.05) | 24 (10.76) | Â | 0.57 (0.26, 1.24) |
| Â | A/G | 71 (47.65) | 108 (48.43) | Â | 0.86 (0.55, 1.34) | A/G | 66 (44.30) | 110 (49.33) | Â | 0.73 (0.47, 1.14) |
| Â | G/G | 11 (7.38) | 26 (11.66) | 0.33 | 0.51 (0.23, 1.33) | G/G | 71 (47.65) | 89 (39.91) | 0.30 | 1 |
Male | A/A | 18 (35.29) | 27 (56.25) | Â | 1 | A/A | 9 (17.65) | 3 (6.25) | Â | 4.43 (1.04, 18.89)** |
| Â | A/G | 25 (49.02) | 18 (37.50) | Â | 2.15 (0.91, 5.09) | A/G | 23 (45.10) | 19 (39.58_ | Â | 1.70 (0.72, 3.99) |
|  | G/G | 8 (15.69) | 3 (6.25) | 0.08 | 4.53 (1.03, 19.91)‡ | G/G | 19 (37.25) | 26 (54.17) | 0.11 | 1 |
| Â | Â | P Homogeneity Test | :0.01 | Â | Â | P Homogeneity Test | :0.01 | Â | ||
Allelic | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Female | A allele | 205 (68.79) | 286 (64.13) | Â | 1 | A allele | 90 (30.20) | 158 (35.43) | Â | 0.76 (0.55, 1.05) |
| Â | G allele | 93 (31.21) | 160 (35.87) | 0.19 | 0.79 (0.57, 1.08) | G allele | 208 (69.80) | 288 (64.57) | 0.14 | 1 |
Male | A allele | 61 (59.80) | 72 (75.00) | Â | 1 | A allele | 41 (40.20) | 25 (26.04) | Â | 1.97 (1.07, 3.62) |
| Â | G allele | 41 (40.20) | 24 (25.00) | 0.02 | 2.11 (1.14, 3.91) | G allele | 61 (59.80) | 71 (73.96) | 0.03 | 1 |
| Â | Â | P Homogeneity Test | :0.01 | Â | Â | P Homogeneity Test | :0.01 | Â | ||