Suggestive evidence of associations between liver X receptor β polymorphisms with type 2 diabetes mellitus and obesity in three cohort studies: HUNT2 (Norway), MONICA (France) and HELENA (Europe)

Table 2 Genotype distribution for the 5 LXRβ; SNPs in individuals with and without T2DM from the HUNT2 study and ORs [95% CI] of T2DM.

	Genotype	Controls (n = 1986)		T2DM (n = 835)		Crude p	Adjusted OR	[95% CI]	Adjusted p
		n	Frequency	n	Frequency
rs17373080	CC	815	0.41	381	0.46
	CG	934	0.47	367	0.44	0.08	0.82	[0.69-0.98]	0.03
	GG	236	0.12	87	0.10
	Total	1985		835
rs56151148	CC	1655	0.84	684	0.82
	CT	303	0.15	141	0.17	0.23^a	1.15	[0.92-1.45]	0.22
	TT	12	0.01	9	0.01
	Total	1970		834
rs2695121	CC	629	0.32	262	0.31
	CT	970	0.49	401	0.48	0.79	1.02	[0.85-1.23]	0.80
	TT	382	0.19	170	0.20
	Total	1981		833
rs2303044	CC	1726	0.87	733	0.88
	CT	242	0.12	96	0.12	0.43^a	0.84	[0.65-1.09]	0.20
	TT	12	0.01	2	0.00
	Total	1980		831
rs3219281	CC	1624	0.83	696	0.84
	CT	323	0.16	128	0.15	0.27^a	0.87	[0.69-1.10]	0.25
	TT	21	0.01	4	0.00
	Total	1968		828

ISSN: 1471-2350