Characterisation of CYP2C8, CYP2C9 and CYP2C19 polymorphisms in a Ghanaian population

BMC Medical Genetics

Table 3 Allele frequencies of CYP2C8, CYP2C19 and CYP2C19 variants in a Ghanaian and other previously studied populations

	CYP2C8 *2	CYP2C8 *3	CYP2C8 *4	CYP2C9 *2	CYP2C9 *3	CYP2C9 *4	CYP2C9 *5	CYP2C9 *11	CYP2C19 *2	CYP2C19 *3
African
Ghanaian	0.17	0	0	0	0	0	0	0.02	0.06	0
Ghanaian	0.17 [23]	0 [23]	0 [23]
Zanzibaris	0.14 [20]	0.02 [20]	0.006 [20]
Burkinabe	0.115 [19]	0.004 [19]	0 [19]
Beninese				0 [15]	0 [15]	0 [15]	0.02 [15]	0.03 [15]	0.13 [15]	0[15]
Ethiopian				0.043 [24]	0.023 [24]		0 [24]
Zimbabweam									0.13 [34]	0[34]
African American	0.18 [6]	0.02 [6]		0.033 [18]	0.023 [18]	0 [18]	0.01 [18]	0.02 [18]	0.25 [33]	0 [33]
Caucasian §	0 - 0.004 [2]	0.095 - 0.17 [2]	0 - 0.075 [2]	0.08 - 0.191 [2]	0.03 - 0.17 [2]	0 - 0.004 [15]	0 [2]		0.09 [15] - 0.14 [42]	0
Asian §	0 [2]	0 [2]	0 [2]	0 - 0.001 [2]	0.011 - 0.068 [2]				0.23 [33] - 0.305 [43]	0.085 [43]

§ The lowest and the highest allele frequencies for Caucasian and Asian populations

ISSN: 1471-2350