Figure 1

Pairwise linkage disequilibrium between the six genotyped SNPs in a 14 kb region of PIN1 (Haploview 4.1) for combined group (n = 321) of all patients (LOAD, EOAD and FTD) and controls. Numbers inside the squares represent the D' value expressed as a percent. Squares without numbers represent D' values of 1.0, indicative of complete linkage disequilibrium. Darker-shaded squares represent pairs with LOD score for linkage disequilibrium of = 2, light grey squares represent D' = 1 but LOD <2, and white squares represent LOD <2 and D' <1.0.