Fig. 1From: Characterization of an N-terminal Nav1.5 channel variant – a potential risk factor for arrhythmias and sudden death?Detection of the SCN5A variant p.(Ser106Gly) in a patient with aborted cardiac arrest. a Schematic representation of the Nav1.5 channel and localization of the detected N-terminal variant. b Alignment of a partial N-terminal sequence among mammals. The affected amino acid is indicated in red. c Assessment of the genetic variant by in silico prediction toolsBack to article page