Fig. 5

Weighted gene co-expression network construction and identification of the brown module containing GSK3B. a Clustering dendogram of samples. b The scale independence and the mean connectivity of the weighted gene co-expression network analysis (WGCNA) analysis of peri-implantitis. Testing the scale free topology when β = 32. c Clustering dendrograms and modules identified by WGCNA. d Correlation between module eigengenes and clinical traits. The brown module containing GSK3B is selected. e The cluster tree and eigengene adjacency heatmap between modules. f The scatter diagram of gene significance (GS) vs module membership (MM) in the brown module of peri-implantitis. Gene GSK3B has been highlighted in red dot, the cutoff of brown module membership = 0.88, the cutoff of gene significance for peri-implantitis = 0.35