Table 2 Summary of cytogenetic and molecular findings
From: KANK1-NTRK3 fusions define a subset of BRAF mutation negative renal metanephric adenomas
Total # of cases | Patients | Karyotype n = 28 | BRAFV600E n = 24 (%) Mutation Wild Type | FISH for t(9;15) n = 20 (%) | |
|---|---|---|---|---|---|
28 | 6 (21%) | 15 (62%) | 9 (38%) | 2 (10%) | |
> 30 years | 20 | 3 | 13 | 3 | 0 |
< 30 years | 7 | 3 | 2 | 5 | 2 (100%) |
Unknown | 1 | 0 | 0 | 1 | Â |
Female (median age in years) | 17 (52) | 3 | 8 | 5 | 1 |
Male (median age in years) | 10 (53.5) | 3 | 7 | 3 | 1 |
Unknown | 1 | 0 | 0 | 1 | 1 |