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Table 1 Clinical, pathological, cytogenetic, and molecular findingsa

From: KANK1-NTRK3 fusions define a subset of BRAF mutation negative renal metanephric adenomas

Case no.

Age range years

Gender

Tumor Size (cm)

Laterality

Karyotype

BRAF Status

t(9;15)(p24;q24) FISH

1.

21–30

F

2

Right

46,XX,t(9;15)(p24;q24)

Wild type

Fusion Present

2.

21–30

F

3

Left

46,XX,t(6;22)(q26;q11.2)

Wild type

Normal

3.

41–50

M

12

NA

46,XY

V600E Mutation

Normal

4.

51–60

F

1.4

Left

46,XX

V600E Mutation

Normal

5.

51–60

M

3

Right

46,XY

V600E Mutation

Normal

6.

31–40

F

6.7

Left

NA

V600E Mutation

Normal

7.

61–70

F

NA

Right

NA

Uninformative

Uninformative

8.

51–60

M

NA

NA

NA

V600E Mutation

Uninformative

9.

51–60

F

0.5

Right

NA

Uninformative

Uninformative

10.

61–70

F

5.1

Right

NA

V600E Mutation

Normal

11.

31–40

F

3.4

Left

NA

V600E Mutation

Normal

12.

1–10

M

1.7

Right

46,XY,t(9;15)(p24;q24),inv.(12)(q13q15)

Wild type

Fusion Present

13.

1–10

M

1.5

Right

NA

V600E Mutation

Normal

14.

31–40

M

4.3

NA

NA

V600E Mutation

Normal

15.

11–20

M

7

Right

NA

Wild type

Normal

16.

NA

NA

NA

NA

NA

Wild type

Normal

17.

51–60

F

NA

Left

NA

Wild type

Normal

18.

51–60

F

5

NA

NA

Uninformative

Uninformative

19.

71–80

M

1.8

Right

NA

Wild type

Normal

20

21–30

F

2

NA

NA

Wild type

Uninformative

21.

61–70

F

4

NA

NA

Wild type

Uninformative

22.

71–80

F

2.5

NA

NA

V600E Mutation

Normal

23.

51–60

F

5

NA

NA

Uninformative

Uninformative

24.

51–60

F

3

NA

NA

V600E Mutation

Normal

25.

11–20

F

3

Right

NA

V600E Mutation

Normal

26.

41–50

F

1.5

NA

NA

V600E Mutation

Uninformative

27.

61–70

M

8

NA

NA

V600E Mutation

Normal

28.

61–70

M

3

NA

NA

V600E Mutation

Normal

  1. aAbbreviations: NA indicates not available, FISH Fluorescent in situ hybridization