From: KANK1-NTRK3 fusions define a subset of BRAF mutation negative renal metanephric adenomas
Case no. | Age range years | Gender | Tumor Size (cm) | Laterality | Karyotype | BRAF Status | t(9;15)(p24;q24) FISH |
---|---|---|---|---|---|---|---|
1. | 21–30 | F | 2 | Right | 46,XX,t(9;15)(p24;q24) | Wild type | Fusion Present |
2. | 21–30 | F | 3 | Left | 46,XX,t(6;22)(q26;q11.2) | Wild type | Normal |
3. | 41–50 | M | 12 | NA | 46,XY | V600E Mutation | Normal |
4. | 51–60 | F | 1.4 | Left | 46,XX | V600E Mutation | Normal |
5. | 51–60 | M | 3 | Right | 46,XY | V600E Mutation | Normal |
6. | 31–40 | F | 6.7 | Left | NA | V600E Mutation | Normal |
7. | 61–70 | F | NA | Right | NA | Uninformative | Uninformative |
8. | 51–60 | M | NA | NA | NA | V600E Mutation | Uninformative |
9. | 51–60 | F | 0.5 | Right | NA | Uninformative | Uninformative |
10. | 61–70 | F | 5.1 | Right | NA | V600E Mutation | Normal |
11. | 31–40 | F | 3.4 | Left | NA | V600E Mutation | Normal |
12. | 1–10 | M | 1.7 | Right | 46,XY,t(9;15)(p24;q24),inv.(12)(q13q15) | Wild type | Fusion Present |
13. | 1–10 | M | 1.5 | Right | NA | V600E Mutation | Normal |
14. | 31–40 | M | 4.3 | NA | NA | V600E Mutation | Normal |
15. | 11–20 | M | 7 | Right | NA | Wild type | Normal |
16. | NA | NA | NA | NA | NA | Wild type | Normal |
17. | 51–60 | F | NA | Left | NA | Wild type | Normal |
18. | 51–60 | F | 5 | NA | NA | Uninformative | Uninformative |
19. | 71–80 | M | 1.8 | Right | NA | Wild type | Normal |
20 | 21–30 | F | 2 | NA | NA | Wild type | Uninformative |
21. | 61–70 | F | 4 | NA | NA | Wild type | Uninformative |
22. | 71–80 | F | 2.5 | NA | NA | V600E Mutation | Normal |
23. | 51–60 | F | 5 | NA | NA | Uninformative | Uninformative |
24. | 51–60 | F | 3 | NA | NA | V600E Mutation | Normal |
25. | 11–20 | F | 3 | Right | NA | V600E Mutation | Normal |
26. | 41–50 | F | 1.5 | NA | NA | V600E Mutation | Uninformative |
27. | 61–70 | M | 8 | NA | NA | V600E Mutation | Normal |
28. | 61–70 | M | 3 | NA | NA | V600E Mutation | Normal |