Skip to main content

Table 5 Characteristics and allelic frequency of the subjects by number of methylated genes

From: Effect of DNMT3A polymorphisms on CpG island hypermethylation in gastric mucosa

number of methylated gene

0

1

2

3

4

number of sample

123

156

131

75

25

mean age ± SD

59.8 ± 14.9

59.9 ± 13.3

59.5 ± 14.1

61.9 ± 12.3

68.2 ± 10.3a

male: female

66: 57

100: 56

71: 60

46: 29

14: 11

HP infection status

53/123

89/156b

89/131c

67/75c

23/25c

(rs6733868 C > G)

 CC

36

56

61d

44c

15e

 CG

57

82

53

24

8

 GG

30

18f

17g

7h

2

 G allele freuqency

47.6%

37.8%i

33.2%j

25.3%c

24.0%k

(rs13428812 A > G)

 AA

57

93l

82m

61c

20n

 AG

53

57

43

10

3

 GG

13

6o

6

4

2

 G allele frequency

32.1%

22.1%p

21.0%q

12.0%c

14.0%r

  1. a: p = 0.0082, b: p = 0.016, c: p < 0.0001, d: p = 0.0065, e: p = 0.0051, f: p = 0.0063, g: p = 0.023, h: p = 0.0085,
  2. i: p = 0.025, j: p = 0.0011, k: p = 0.0027, l: p = 0.030, m: p = 0.012, n: p = 0.0021, o: p = 0.032, p: p = 0.0091,
  3. q: p = 0.0048, r: p = 0.010 vs. 0 group