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Table 3 Association between MIF rs755622 and CDKN2A methylation

From: Influence of MIF polymorphisms on CpG island hyper-methylation of CDKN2A in the patients with ulcerative colitis

 

Genotype

GG vs. GC + CC

GG + GC vs. CC

GG

GC

CC

adjusted OR* (95%CI); p value

adjusted OR* (95% CI); p value

p14-UM (105)

68

32

5

reference

reference

p14-M (54)

25

25

4

2.16 (1.08–4.32); p = 0.030

2.30 (0.52–10.3); p = 0.27

p16-UM (89)

57

28

4

reference

reference

p16-M (70)

36

29

5

1.90 (0.974–3.69); p = 0.060

2.25 (0.52–9.69); p = 0.28

  1. *by logistic regression analysis after adjustment for age, gender, clinical type and disease extension
  2. UM Unmethylated, M Methylated