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Fig. 2 | BMC Medical Genetics

Fig. 2

From: Unannotated single nucleotide polymorphisms in the TATA box of erythropoiesis genes show in vitro positive involvements in cognitive and mental disorders

Fig. 2

Measuring the kinetics of TBP binding to TATA-containing ODN N2 identical to the HBB promoter in healthy people. Legend: a Dependences of reaction rates on ODN N2 concentrations; b electropherograms from which these curves were derived. TBP concentration was 0.4 nM in all the experiments; the concentrations of a TATA-containing ODN that we used are indicated. TBP–TATA-associated isotherms and ka and kd values were inferred from the electropherograms using GraphPad Prism 5 software

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